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Interestingly, although NOS enzymatic activity remained normal during initial disease progression [130], the bioavailability of NO was already reduced [129]

Historical Background and Scientific Context Scientific interest in DSIP emerged during the twentieth century as researchers sought to better understand naturally occurring peptide messengers and their role in biological signalling systems

DeutzNEBauerJMBarazzoniRBioloGBoirieYBosy-WestphalAet al

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IGF is also important for production of connective tissue and insuring proper bone density