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Required criteria for ALPS included the presence of lymphadenopathy and/or splenomegaly and elevated TCR + -DNT cells

Initial investigations typically include liver function tests, renal function assessment, and full blood count

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The postulated mechanism for causing such attacks is through stimulation of the porphyrin precursor, delta-aminolevulinic acid (ALA) Laboratory tests: Diclofenac prolongs platelet aggregation without affecting the bleeding time, plasma fibrinogen and factors V and VII to XII

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