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Effect of the interruption of ggt and pepT on GSH degradation Previous studies have indicated that GSH is significantly degraded close to the end of the fermentation process, resulting in a lower GSH production level

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revealed that myocardial ferroptosis occurs during MI [87]

Cells transformed with empty plasmids served as controls for the subtraction of fluorescence background

Then, -GC is combined with Gly through a typical -linkage by the enzyme GSH synthetase (GS), which also requires ATP and Mg 2+ as co-substrates, ultimately resulting in the formation of GSH (Figure 2A) [ 11 ]