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Some comments deserve the questionnaire-based study on 232 hypothyroid patients from Poland (132), a country where 15.8% of women and 2.5% of men suffer from thyroid disease, with an increase of 4.0 percent points in the year 2019 compared to 2014 (132)

Multiple studies have proved that for TMAO to induce inflammatory gene expression in leukocytes and both cell types, nuclear factor kappa B signaling has to be activated [69]

doi: 10.1002/rmb2.12013 106