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While these interactions do not establish direct causality, they provide integrative evidence linking metabolomic alterations to gene networks previously implicated in neurodevelopmental and metabolic regulation

Jun 6 2020;10(3):20190098

Gut microbiota in Parkinsons disease: temporal stability and relations to disease progression

MVD-affected dogs in heart failure have been shown to have significantly higher circulating levels of TMAO in their blood serum compared to healthy dogs and to dogs with pre-CHF MVD

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48 Parkinsons disease Aside from the aggregation of misfolded -synuclein in the intracellular Lewy bodies, a major neuropathological hallmark of PD is the loss of dopaminergic neurons within the SN