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[26] [39] In 2013, overdose on amphetamine, methamphetamine, and other compounds implicated in an "amphetamine use disorder" resulted in an estimated 3,788 deaths worldwide (3,4254,145 deaths, 95% confidence)

For those without an absorption problem, research suggests that high-dose oral B12 supplements can be as effective as injections in raising and maintaining B12 levels

Furthermore, a recent study reported a small molecule, KDS12025, which can increase the activity of hemoglobin pseudoperoxidase by 100fold even at low hemoglobin levels

GPR30 is overexpressed in post-puberal testicular germ cell tumors

In such cases, supplementation with sublingual B12 may be recommended as a means of restoring B12 levels

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