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14 However, the data are confounded by past or concomitant use of phototherapy or other immunosuppressive agents

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As cartilage degrades, proteoglycan content decreases, leading to thinner, stiffer, and more vulnerable joint surfaces

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The bodys immune system attacks the cells in the stomach lining responsible for producing a protein called intrinsic factor , which is necessary for the absorption of vitamin B12 in the small intestine