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Oral peptide products exist because consumer demand for "needle-free" options creates a market, not because the science supports efficacy

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[42] In the liver, the carboxylation of cytosolic pyruvate into intra-mitochondrial oxaloacetate is an early step in the gluconeogenic pathway which converts lactate and de-aminated alanine into glucose, [40] [41] under the influence of high levels of glucagon and/or epinephrine in the blood

While early trial results suggest retatrutide may be even more effective than current weight-loss medications, some providers are irresponsibly offering it to patients based on the assumption that approval is inevitable