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Tumour Biol 39:1010428317691429 Lpez de la Oliva AR, Campos-Sandoval JA, Gmez-Garca MC et al (2020) Nuclear translocation of glutaminase GLS2 in human cancer cells associates with proliferation arrest and differentiation

By separating the lipolytic C-terminal region, researchers produced a compound with concentrated fat-metabolism activity and a significantly reduced side-effect profile compared to recombinant GH particularly with respect to insulin sensitivity and IGF-1 axis stimulation, which are primary concerns with full GH administration in research models

Researchers have proposed that high folic acid intake may mask certain signs of vitamin B12 deficiency

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Although there is a broad clinical spectrum of glutathione synthetase deficiency, manifestations usually include hemolytic anemia, often include metabolic acidosis, and sometimes include progressive neurologic symptoms as well as other systemic signs (eg, respiratory distress, sepsis, hyperbilirubinemia) (62