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These discoveries provide novel therapeutic options for patients with multiple sclerosis, complementing existing immunosuppressive strategies

As the name suggests, this is a form of cell death caused by copper, in which copper ions directly bind to protein lipoylation components in the tricarboxylic acid circulation pathway, causing abnormal aggregation of lipoylated proteins and loss of iron-sulfur cluster protein, resulting in protein toxic stress responses and cell death (172)

So far two major methods have been used

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