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that concentration is required for vitamin C to compete efficiently with the reaction of NO with superoxide

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Despite encouraging results from early trials, larger and well-designed randomised studies are needed to confirm its efficacy, define optimal dosing, and evaluate long-term safety particularly in elderly and comorbid populations

Active ingredients of Chinese medicine Salvianolic acid (salvianolic acid A and salvianolic acid B) is an active ingredient extracted from the Chinese medicine Salvia miltiorrhiza (Danshen), which has effects on oxidative stress, myocardial fibrosis, platelet aggregation, coagulation, thrombosis, endothelial dysfunction and inflammation in the cardiovascular system ( 1/Smad2/3-mediated collagen deposition and suppressed the thioredoxin-interacting protein (TXNIP)/NLRP3/IL-1 and IL-18 signaling pathways, significantly improving cardiac function and reducing susceptibility to AF and duration ( Tanshinone IIA is a fat-soluble active ingredient of salvia miltiorrhiza, with anticoagulant, anti-inflammatory, antioxidant, anti-fibrotic, and immunomodulatory effects ( Panax notoginseng saponins (PTS) is the main active component of the Chinese medicine Panax notoginseng, which is often used clinically in the treatment of myocardial ischemia, atherosclerosis, coronary artery disease, and myocardial fibrosis

doi: 10.3390/v13112132 131 KaklamanosA.BelogiannisK.SkendrosP.GorgoulisV

Opportunities and challenges for inhalable nanomedicine formulations in respiratory diseases: a review