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Kwak C, Kim HK, Kim EC, Choi MS, Kim HH

Weber AE, Gallo MC, Bolia IK, Cleary EJ, Schroeder TE, Hatch GFR

Meso-tetra (4-hydroxyphenyl) porphyrin has been chosen for its excellent optical properties and well-established metal chelation capability, which makes it an ideal candidate for optical sensing.Upon exposure to mercury ions solution, the sensor exhibits evident and typical variations in the Soret and in the Q bands, enabling effective detection

Only a small fraction of Mn, in the form of Mn 3+ bound to transferrin, enters the cell through transferrin receptor-mediated endocytosis ( in vitro and in vivo , as Mn uptake was enhanced by calcium channel activators and inhibited by blockers ( 2+ -dependent inhibition of choline uptake in rats

Because the utility of polymeric prodrugs depends heavily on their degradation kinetics, future studies will incorporate detailed characterization of GRIP cleavage and payload release kinetics, for example using HPLC-MS analysis, to better inform in vivo dosing strategies

The goal of lifestyle medicine is to prevent the occurrence and recurrence of disease by improving sleep hygiene and diet, increasing physical exercise, avoiding sedentary behavior, increasing social support, and improving mood