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It is known as the partition ratio

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Adding Equation 16.63 and Equation 16.64 and canceling H 2 CO 3 from both sides give the following overall equation for the reaction of CO 2 with water to give a proton and the bicarbonate ion: Equation 16.65 The K value for the reaction in Equation 16.65 is the product of the true ionization constant for carbonic acid ( K a ) and the equilibrium constant ( K ) for the reaction of CO 2 (aq) with water to give carbonic acid

From the first cautious 0.5mg test dose through the full 12mg maintenance protocol, mapped across every common vial size and reconstitution volume, with the exact syringe lines marked for each step

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