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Others can do it from certain medicines

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A previous study reported that activities of antioxidant enzymes such as SOD, CAT, GPX, GSH reductase and glutathione-S-transferase were significantly increased in knee OA synovial fluid [148]

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The interactions between high estrogen levels and the gut microbiota (GM) detrimentally affect embryo implantation and fertility by altering the cervical vaginal microenvironment, such as increased pH, bacterial overgrowth, and increased levels of inflammatory factors