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Ann N Y Acad Sci 1982;393:361-8

Available research suggests a favorable safety profile, with no major toxicity saw even at high doses in animal studies, no evidence of carcinogenic effects, no hormonal disruption, and good tolerability across many use routes

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This is not to say that you wont ever need to take a B-12 supplement if you are a VSG, Lap-Band or DS patient

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This is vital for maintaining the integrity of the genetic material in oocytes