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10.1021/om500317b 117 PettinariR.MarchettiF.PettinariC.CondelloF.PetriniA.ScopellitiR.et al (2015)

However, it doesn't address the underlying immune dysregulation

A shift from small molecules towards biopharmaceuticals in major pharmaceutical companies is likely to lead to increased efforts in developing and evaluating strategies to improve the delivery of large molecules to the brain