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doi: 10.1523/jneurosci.1409-19.2019

Peer review Peer review information Nature Reviews Nephrology thanks Dianne McKay, who co-reviewed with Stephanie Almeida

28.4% of patients had potentially disease-causing variants of ABCB4, ABCB11, and ATP8B1genes with different liver disease phenotypes

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Vitamin C, a powerful antioxidant that your body cannot produce, occurs in many fruits and vegetables, including sulfurous foods like broccoli, but its content can fluctuate by season

Because N-acetylation is a minor pathway of drug metabolism, pharmacogenetics remained of largely academic interest until the late 1970s, when it was found that the cytochrome P450 isoenzyme CYP2D6, which is involved in the phase 1 metabolism of 2025% of all drugs, showed functionally important genetic polymorphisms