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Immunostaining revealed mixed cell populations with many undifferentiated hPSCs and mesoderm cells, and DE markers SOX17 and FOXA2 were expressed at lower levels compared to the Activin A-based control (CA)

Small sample sizes can make drugs look much more or less effective than what they really are

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The preclinical research particularly for tissue healing, gut protection, and anti-inflammatory effects is impressive and warrants further investigation

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What Needs to Be in Place Before a First-in-Human Trial Begins Before entering a First-in-Human trial, a drug candidate must be supported by a comprehensive package of scientific, non-clinical and quality evidence