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For example, wild-type TP53 is able to inhibit glycolysis by suppressing the expression of GLUT1, GLUT3, and GLUT4 (160, 161), and regulating the expression of enzymes involved in the glycolytic pathway, such as HK2 (162), phosphofructokinase 1 (PFK1) (163), phosphoglycerate mutase (PGM) (163), pyruvate dehydrogenase (PDH), parkin 2 (PARK2) (164), and pyruvate dehydrogenase kinase (PDK2) (165)

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Lung tissues of mice infected for 1 day or 4 weeks were collected and used to detect bacterial burden

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A 105 , 99549960 (2001) Jorgensen, W.L., Maxwell, D.S., Tirado-Rives, J.: Development and testing of the OPLS all-atom force field on conformational energetics and properties of organic liquids

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TRX2= thioredoxin 2

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