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doi: 10.1186/s40364-024-00620-x 325

HDAC6 inhibitor-loaded brain-targeted nanocarrier-mediated neuroprotection in methamphetamine-driven Parkinsons disease

Notably, this egress site is covered by a loop, with two histidine residues on this loop interacting with the egress-site ion, crucially regulating its release

In summary, functioning as intrinsic m7G-recognizing proteins within mRNA, QKIs orchestrate the regulation of target mRNA metabolism and modulate cellular chemoresistance, making them as promising candidates for therapeutic intervention