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High expression levels of COX-2 and P300 are associated with unfavorable survival in laryngeal squamous cell carcinoma

7.2 What Does a Low GSH/GSSG Ratio Indicate

Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology

[DOI] [PubMed] [Google Scholar] 79.Borchelt D

Due to the exhaustion of cellular and extracellular GSH caused by numerous GSH-consuming pathways the severe inflammation and oxidative stress triggered by the viral infection steals GSH from crucial functions like NO-dependent vasodilatation, disallowing the patient of being protected from an inflammation that can become fatal

Consequently, macrophages derived from healthy controls were transfected with two different sequences of GPX1 SiRNA to knockdown (KD) protein expression