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Something old, something new and something borrowed: Emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation

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The practical result is that it drives GLUT4 transporters to the muscle cell surface and pulls glucose out of the blood within about 10 minutes, just like insulin does (Bilan et al., 1992)

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Mitochondrial volume and TMRM intensity quantification were determined using a similar MATLAB script as previously reported [46]

L2-Cmu does not perturb glucose homeostasis in older mice We then evaluated effects of chronic IGF-1R mAb treatment on energy and glucose homeostasis in an initial cohort of older mice