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Monitoring kidney function, staying hydrated, and using appropriate dosing helps maintain safety

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Sukenaga et al

237 Aaltonen, K., Hmlinen, M

For nanomaterials-enhanced glucose metabolism intervention, nanotechnology provides innovative solutions to modulate tumor glucose metabolism by blocking glucose uptake, inhibiting glucose transporter [40, 41], glucose depletion [42,43,44], modulating glycolytic enzymes [45, 46], reprogramming metabolic pathways [47], and combining glucose metabolic regulation with other therapies [48, 49]

Figure 8 The HNF4 agonist NCT improves Nr1i3 transcription and CAR activity NCT has previously been shown to specifically target HNF4 and provide protection in models of NAFLD and peritoneal sepsis (65, 66)