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For functional analysis, SEED Subsystems 46 and KEGG 18 databases were applied to explore the microbial functions in DW samples

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Results: Rs6461378-T positively associated with histologic NAFLD in the EPoS consortium cohort ( P =0.017), confirming the prior genetic association results and suggesting a possible direct impact on human liver disease

Finally, it has been shown that persistent DNA damage signaling contributes to the secretion of the SASP factors, highlighting the role of oxidants in senescent cells and their impact on the organism (Rodier et al., 2009)