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The Phase 2b trial (PMID: 23714218) failed to demonstrate significant weight loss compared to placebo over 12 weeks, despite adequate sample size and dosing

These results suggested that the upregulation of GPX1 promotes, while the deficiency of GPX1 suppresses, the survival of SGNs after peroxynitrite injury

Vitr Cell Dev Biol - Anim (2019) 55(4):2529

Figure 9, and further details of the advantages and disadvantages of each method are listed in Supplementary Table 1

144-01993) in 0.2 M phosphate buffer (pH 7.4) with sodium succinate

DTI is a magnetic resonance imaging (MRI) technique that differentiates the degree and direction of water diffusion within an allotted space (Pierpaoli and Basser, 1996)