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Este cambio metablico se debe a la accin del pptido sobre la va de metilacin de la nicotinamida , que aumenta la disponibilidad intracelular de NAD+, facilitando as un mayor metabolismo oxidativo

In particular, the E-domains were enriched in disorder-promoting amino acids, and by bioinformatic analyses, we demonstrated that the E-domains are IDRs, which were also confirmed by the limited proteolysis approach (Figs 1 and S1C)

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Human growth hormone is a 191-amino acid protein with distinct functional regions

While side effects are possible, theyre usually mild and temporary