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Intriguingly, in another study, Calnan et al

Because the active ingredient is "hidden" inside a lipid shell, it does not interact with the stomach lining in the same way that raw powders might

Six chemicals known to induce kidney tumors in rats, including trichloroethylene, were examined for their ability to induce DNA fragmentation and the formation of micronuclei in primary cultures of rat and human kidney cells and in kidneys of intact rats

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And so its bonded to orotic acid

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