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12 GM-targeted therapies: clinical evidence and critical evaluation Deriving from the existing comprehensive studies on the gut-bone axis, the modulation of the GM presents a promising and increasingly evidence-based strategy for the management of OP in clinical settings

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coli K12 (BW25113), HaloTag was cloned onto an expression vector pQE-30 (Genscript) and codon-optimized for expression in E

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This treatment efficacy was due to ARBM-101-enforced systemic copper excretion as unraveled by in vivo 64 Cu- PET-scans

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