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Indicatively, the demonstrated leading role of rapid heart disturbances and general vascular failure in the major vessels-induced occlusive syn- dromes [ 14 20 ] and in occlusion-like syndrome with major intoxication (alcohol, lithium) or maintained severe intra-abdominal hypertension [ 21 23 ] means in the isoprenaline-treated rats, isoprenaline was detected as an early syndrome of multiorgan failure, peripherally and centrally

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