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Methods Enzymol 105:121126

Can help protect cells from damage caused by free radicals

The observed alterations in energy and lipid metabolism present promising therapeutic avenues for alleviating symptoms in these patient populations

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Parseghian CM, Loree JM, Morris VK, Liu X, Clifton KK, Napolitano S, Henry JT, Pereira AA, Vilar E, Johnson B, Kee B, Raghav K, Dasari A, Wu J, Garg N, Raymond VM, Banks KC, Talasaz AA, Lanman RB, Strickler JH, Hong DS, Corcoran RB, Overman MJ, S K

The C-CRD of Yap1 consists of a leucine-rich export signal (NES) and two cysteine-rich domains (CRD) positioned at the N- and C-termini