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[1] [2] Elevated methylmalonic acid levels may also indicate a deficiency

Therefore, the first place you need to look when the benefits of a methyl-B12 shot seems to wear off too soon is to retry the shots at the same dose and frequency but make the angle of attack much more severe, much closer to the horizontal plane, just under the skin

It needs to be made clear that frequent B12 injections are necessary for recovery from nerve damage caused by lack of B12 and that each patient has a different requirement based on their individual experience

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The commonly recommended timing, morning on an empty stomach 30-60 minutes before eating, maximizes fat oxidation effects but may increase nausea in sensitive individuals