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Paraffin-embedded brain blocks were chosen upon the presence of at least one active and one mixed active/inactive (chronic) lesion

It was reported that GST- inactivation was often observed in human cancers (liver cancer, breast cancer, prostate cancer, leukaemia)

However, by increasing glutamate and excessive activation of glutamate receptors, it could be a critical strike to dopaminergic neurons in PD patients

Many patients describe pain from clothing, bedsheets, a light breeze, or gentle touch

36 WangM.HanY.WangX.LiangS.BoC.ZhangZ.et al (2021)

Blood work if indicated checking overall health, nutritional status (vitamin D common deficiency affecting bone health), inflammatory markers