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Several studies reported that GSTP1 overexpression enhances cancer cell proliferation, invasion, and formation of metastatic nodules, while suppression of the enzyme has the opposite effect, which suggests GSTP1 acts as a positive regulator of metastatic processes (FeiFei et al

Ferroptosis, a new type of regulated cell death, is triggered by the iron-catalysed process of lipid peroxidation initiated via nonenzymatic (Fenton reactions) and enzymatic mechanisms (lipoxygenases) [5]

Furthermore, by reacting with PUFA, O 2 and OH radicals initiate a chain reaction, generating other incredibly reactive ROS that interact with cellular proteins and nucleic acids [126]

Involved in cellular metabolism, Acetyl L-Carnitine helps to increase energy production in the mitochondria

10.1007/s10554-021-02171-w 53

Low levels of both can point to broader malabsorption