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Resistance to cisplatin, but not oxaliplatin, appears to be partly mediated through loss of function in the MMR proteins (hMLH1, hMLH2, or hMSH6), which recognize platinum-DNA adducts and initiate apoptosis

10.1016/j.lfs.2020.118375 174

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flank: p = 0.1310) (j) and cystine (no tumor vs

Patient 2 is a 35-year-old female with focal unaware seizures from right hemisphere with whole-cerebral spread status post long-term vagal nerve stimulator placement in 2013 (6 years prior to the current study) and no prior surgical intervention, currently on lamotrigine, carbamazepine, and topiramate