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IL-23 inhibitors, including mirikizumab, have demonstrated impressive efficacy in clinical trials, resulting in substantial improvements in psoriatic skin lesions (Blauvelt et al

EPA is metabolised by 5-LOX and modified forms of COX-2 to produce E-series resolvins (Rv) ( Reference Oh, Dona and Fredman 63 ) , whereas 12/15-LOX converts DHA to the D-series Rv, protectins (PD1) and the macrophage-specific maresin (MaR 1 )

Antioxidants and Aging Oxidative stress also appears to increase with age, and may play a role in the aging process itself

doi:10.1016/s0140-6736(19)30941-9

Metabolic and Biotransformation Effects on Dietary Glucosinolates, Their Bioavailability, Catabolism and Biological Effects in Different Organisms

Altered glycolysis and mitochondrial respiration in a zebrafish model of dravet syndrome