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The scRNA-seq analysis revealed a decreased NUPR1 expression in all cell types in IPF compared to control (Supplemental Fig

Topical scalp: 0.5 % solution, 12 ml twice daily for at least 6 months

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The combination eliminates the need for two separate injections, reduces total injection volume, and ensures consistent dosing ratios optimized for synergistic effects

It remains to be further investigated, whether it is possible to avoid blunting of the inhibitory action by other types of inhibitors, by their combination or by combination of the diverse therapeutic modalities to efficiently limit propagation of tumor cells