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longum, Bifidobacterium breve, Lactobacillus acidophilus, Lactobacillus gasseri, Lacticaseibacillus rhamnosus, Lactiplantibacillus plantarum subsp

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doi: 10.3390/compounds3010005 89 ArrudaTRJuniorBRDCMarquesCSBernardesPCMagalhesCGPinheiroPF

31 , 10371047.e1034 (2021)

215 With age, the reduced pool of nave T cells may impair the ability of the immune system to detect these antigens, creating what is referred to as holes in the repertoire. This limitation could reduce the effectiveness of immunotherapies targeting neoantigens