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Its primary role is to combat harmful free radicals, bolster the immune system, and aid in detoxification processes

For instance, calibrated intratumoral H 2 O 2 combined with radiotherapy activated dendritic-cell (DC)/T-cell responses and elicited an abscopal effect, enhanced by PD-1 blockade [236]

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pseudomallei is able to exploit host GSH as a spatio-temporal cue to transcriptionally turn on its T6SS5 cluster at the precise moment for intercellular spreading only when the bacterium has exited the phagosome [3]

Non-alcoholic fatty liver disease (NAFLD): Oxidative stress and glutathione depletion are characteristic findings in NAFLD and its more severe form, non-alcoholic steatohepatitis (NASH)

10.3389/fphar.2022.823881 45 ChangW