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The hexabody did not compete in vitro with Daratumumab or Isatuximab, but strongly inhibited the cyclase activity of the target

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However, the use of medicinal plants with antioxidant properties has been exploited for their ability to treat or prevent several human pathologies in which oxidative stress seems to be one of the causes

In addition, tryptophan depletion and kynurenine accumulation induce the formation of immunosuppressive regulatory T cells (Tregs), leading to tumor growth (Heng et al., 2016)

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Nanozyme-based therapies for inflammatory immune disorders: opportunities and challenges