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Edlow, A

Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway

Future studies are needed, particularly in clearly defined organ-involved settings such as lupus nephritis, to combine single-cell analysis, spatial transcriptomics, and metabolic flux analysis in order to distinguish the pathogenic driving role of metabolic alterations from their role as accompanying biomarkers

Overall, the diverse mechanisms of these nanomaterials underscore their potential as multifunctional agents in managing oxidative stress and inflammation in IVDD, highlighting the need for ongoing research to optimise their clinical applications

Adults interested in antioxidant-based nutritional supplements

Livneh, I