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An APOE-dependent molecular signature is commonly observed in AD-associated microglia

doi: 10.27213/d.cnki.glnzc.2023.000638 55 JiangLHickmanJHWangS-JGuW

Asian Pac J Cancer Prevent 22(12):39593965 Al-Saaidi JAA, Dawood KA, Latif AD (2012) Immunomodulatory effect of Nigella sativa seed extract in male rabbits treated with dexamethasone

BDNF Upregulation One of the most well-characterized mechanisms involves upregulation of brain-derived neurotrophic factor (BDNF), the most abundant and important neurotrophin in the central nervous system that supports neuronal survival, growth, differentiation, synaptic plasticity, and cognitive function

In these cells, RSL3 potency was also tightly correlated with the degree of proliferative arrest (Pearson R 2 = 0.95, p 4) in both ferroptosis-sensitizing conditions (Figure S7C)