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As PARK2 mice are prone to DA neurodegeneration following complex I inhibition 45 , we hypothesized that rotenone would deplete dopamine in the midbrain

doi: 10.1038/s41580-021-00390-6 12 Espino-GonzalezEDalbramEMounierRGondinJFarupJJessenNet al

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351 Details of other promising candidates under active clinical investigation in the past five years are presented in Table 2, with a more comprehensive list of drugs provided in Table S1