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Suster S, Moran CA, Rice DC

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And some of these cells can synthesize the biologically active form of vitamin D (1,25-dihydroxyvitamin D), which suggests the active form is important in the central nervous system

However, the study found that anti-HPi2-driven CAR-Tregs were unsuccessful due to their non-specificity for human pancreatic islets and high expression on CD4+ T cells, suggesting future studies should explore alternative islet-specific targets (72)

Silencing NRF2 can significantly reduce the expression of SLC7A11 and heme oxygenase-1 (HO-1) and inhibit ferroptosis (69)