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Thus, in some cases overexpression of GPx1 can result in a loss of necessary ROS to promote protein misfolding, alter vascular responses to hydrogen peroxide, attenuate growth factor-mediated signaling and insulin-mediated metabolism, and, as mentioned above, promote the survival of some cancer cells

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In vivo studies have shown that GPX3 knockdown increases extracellular matrix expression and exacerbates kidney fibrotic lesions following obstructive injury

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How Storage Practices Affect Research Results Stable storage conditions protect chemical integrity