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Importantly, patients were already on glucocorticoid treatment before blood collection for this study, which may explain why higher levels of mRNA were not found for some genes, such as CCL2 , CXCL9 , IL6 , IL17A , CCL1 and TNF in MOD and/or SEV patients compared to CTRL at endpoints Z and A ( Figure S2 and Figure 3 )

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Observations are model-dependent and exploratory

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