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doi: 10.1155/2013/139239 401 OuM-YZhangHP-cTZhouSLiQ-F

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The following month, the Annals of Internal Medicine published a study describing alcoholics who developed liver damage after taking "apparently moderate" amounts of acetaminophen

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Despite extensive research, most therapeutic candidates fail to achieve sufficient CNS exposure due to the restrictive bloodbrain barrier (BBB), which blocks over 98% of small molecules and nearly all biologics from entering the brain parenchyma