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Neurosurgery 75 , S24S33 (2014)

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Nauck MA, Meier JJ, Cavender MA et al (2017) Cardiovascular actions and clinical outcomes with glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors

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These include neutrophil serine proteases (NSPs)neutrophil elastase (NE), proteinase 3 (PR3), CatG, and NSP4as well as mast cell chymase and tryptase and lymphocyte granzymes ( Figure 1 Neutrophils are essential for innate immune defense against invading pathogens and are among the initial mediators of the inflammatory response ( Figure 1 ) ( NSPs participate in immune defenses