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It enhances the expression of uncoupling protein 1 (UCP1), which promotes the conversion of white adipose tissue (WAT) to brown adipose tissue (BAT), generating heat

For example, in individuals with a 46,XY karyotype and 5-reductase deficiency or 17-hydroxysteroid dehydrogenase deficiency diagnosed at birth, current guidelines support assigning sex in accordance with chromosomal and gonadal sex, as is also recommended for individuals with 46,XX CAH