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It is possible that a higher dose may be recommended for individuals who have been diagnosed with a vitamin B-12 deficiency

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Structureactivity relationship for small molecule inhibitors of nicotinamide N -methyltransferase

See our L-Carnitine dosage reference for dose-by-goal guidance.

Suboptimal B12 causes brain fog, difficulty concentrating, mood changes, tingling extremities, and progressive neurological decline

5-Amino-1MQ is a small molecule that inhibits nicotinamide N-methyltransferase (NNMT), an enzyme regulating cellular NAD+ metabolism