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A recent study in mice revealed that curcumin is a neuro-protectant with respect to hemin-induced damage among foremost cultures of cerebellar granule neurons

Few mushrooms, including Gloeophyllum sepiarium have more antioxidant properties by reducing oxidative stress and providing benefits to the human body due to the presence of linoleic acid (46)

plantarum ameliorates the therapeutic impact of Danggui Buxue Tang (DBT), a traditional herbal mixture, on type 2 diabetes mellitus by enhancing the inhibitory activity of -glycosidase and suppressing the radical-scavenging and antiglycation of DPPH

Notably, while KPV may be less potent than -MSH, it still exerts considerable anti-inflammatory effects, particularly in mitigating immediate inflammatory responses

Altogether, these pathways form a tightly integrated network, where oxidative stress, inflammatory signaling, and apoptosis reinforce one another, while regulatory pathways such as Nrf2/HO-1, SIRT1, and -Klotho are suppressed, shifting the cellular balance toward damage and follicular loss